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In the 1/16 Masters match in Madrid, Karen Khachanov will face Tommy Paul. Khachanov doesn't play confidently against top-20 opponents, whereas Paul has been showing consistent results. Although both players have played tiebreaks in their previous matches, Khachanov struggles to close out matches in crucial moments. Taking this into account, it is likely that Tommy Paul will defeat Karen Khachanov in this match.
Prediction for the match between Karen Khachanov and Tommy Paul: Total over 22.5 games. Both tennis players are in good form, which suggests the possibility of a drawn-out match. Karen Khachanov has been showing solid play, while Tommy Paul has been a bit inconsistent. In their previous matches, they have both delivered good results, and I expect this match to be long and competitive.
In the match between Karen Khachanov and the American player, it is advisable to prefer Khachanov. The Russian tennis player is playing no worse than his opponent and has greater potential in this matchup. However, he needs to show more consistency. Taking this into account, it is recommended to predict that the total points scored in this game will exceed the set total.