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In the match between Frances Tiafoe and Alexei Popyrin at the US Open, Tiafoe has the advantage. He is in good form, has shown excellent play in previous tournaments, and has more experience playing on hard courts. Popyrin also plays well, but after a strong victory over Djokovic, he may experience emotional pressure. Tiafoe has the support of the crowd and is likely to secure the win.
Prediction for the match between Francis Tiafoe and Alexei Popyrin: I bet on Popyrin's victory. He is in great form, conquering Montreal and defeating Djokovic. Tiafoe, although strong, is not in the best form. Popyrin will show consistent play and win the match.